Obesity Management: Interventions, Anti-Obesity Drugs, Efficacy, Long-term use, Association with Eating Disorders, and Role of Gender-Socio-Economic Barriers

Saumya Lakshman Gaddalay, Royyuru Kesavi Seshu Priya, Sathvika Reddy Mittapally and Saipriya Thota

 

Abstract

Obesity management involves a comprehensive approach that combines lifestyle interventions, pharmacotherapy, and, in some cases, surgical procedures to address the complex and multifactorial nature of the condition. Lifestyle interventions, including dietary modifications, increased physical activity, and behavioral therapy, remain the cornerstone of treatment, but for individuals who are unable to achieve significant weight loss through these methods alone, anti-obesity drugs offer a valuable alternative. These medications, such as glucagon-like peptide-1 (GLP-1) agonists, orlistat, and phentermine-topiramate, target various pathways related to appetite regulation and energy metabolism. While these drugs can be effective in promoting weight loss, their long-term use remains a topic of ongoing research due to concerns about efficacy over time and potential side effects. Additionally, the relationship between obesity treatments and eating disorders (EDs), particularly binge eating disorder (BED), is an important consideration, as some pharmacological treatments may affect eating behaviors, and individuals with obesity may be at heightened risk for developing or exacerbating EDs. Balancing weight loss goals with the potential for adverse impacts on eating behaviors is crucial for ensuring successful, sustainable obesity management.

Published on: February 03, 2025
doi: 10.17756/jocd.2025-052
Citation: Gaddalay SL, Seshu Priya RK, Mittapally SR, Thota S. 2025. Obesity Management: Interventions, Anti-obesity Drugs, Efficacy, Long-term use, Association with Eating Disorders, and Role of Gender-Socio-Economic Barriers. J Obes Chronic Dis 9(1): 1-12.

 

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